An up-tight lawyer, Lenny Rubins, ( ), has to put his dream retirement on hold when his ailing mother ( ) emotionally blackmails him into reuniting his estranged children for a Jewish holiday. They may be peas from the same pod, but in Lenny's eyes, his grown-up children are certainly not even from the same planet: a ruthless control-freak and hard-nosed capitalist, an outspoken, argumentative eco-warrior committed to the cause, an outer-worldly Buddhist Monk; and to cap it all, a bible bashing born-again Rabbi. While they might quarrel, fight, and perhaps even be starting a war in Africa, they are still family. It is going to take a whole lot of soul-searching and sacrifice for everyone to come together in this comic drama.

In London, the radiologist Gina McVey organizes a surprise birthday party to her father John McVey with her boyfriend Stefan Chambers, her brother Daniel McVey and his girlfriend Kate Coleman. On the next day, she sees herself driving a car on the street and she follows the woman to her apartment, where she finds a picture of her father and her. While driving back, she has a car crash and loses parts of her memory; further, she believes Stefan is another man. Gina decides to investigate what is happening and unravels a dark reality.